Set as Homepage - Add to Favorites

日韩欧美成人一区二区三区免费-日韩欧美成人免费中文字幕-日韩欧美成人免费观看-日韩欧美成人免-日韩欧美不卡一区-日韩欧美爱情中文字幕在线

【eroticism in walt whitman】To treat blindness, doctors put gene

On the morning of March 20,eroticism in walt whitman eye surgeon Jason Comander injected viruses carrying lab-grown genes into the eyes of a boy whose vision had been gradually disappearing.

If all goes as planned, the 13-year-old patient -- who lives with an inherited genetic defect that causes blindness -- will experience an improvement in eyesight in about a month.

After a series of tests, the U.S. Food and Drug Administration (FDA) approved this gene-therapy treatment, called Luxturna, in December 2017.

SEE ALSO: Doctors find virus in a pond, use it to destroy antibiotic-resistant bacteria in man's heart

Three months later, the procedure Comander performed at Massachusetts Eye and Ear served as the first time an FDA-approved gene therapy was used on a person living with an inherited, and incurable, genetic disease. There are no other effective treatments for this specific retinal disease.

"It's a huge step in the right direction," said Comander, associate director of the Inherited Retinal Disorders Service at the Boston-based hospital, in an interview.

"Most of the patients are legally blind by their 20s or 30s," said Comander. "Suffice to say, these are really terrible diseases."

Original image replaced with Mashable logoOriginal image has been replaced. Credit: Mashable

Scientists have been working on this novel type of treatment for decades, including as part of FDA trial programs. Comander notes the treatment affects different patients in different ways. Sometimes the vision improvement is dramatic. One previous patient, from an earlier FDA trial, no longer needed to attend a specialized school for children with blindness, Comander said.

"This has been a dream of the field for 30 years, and there have been sobering setbacks," said Tim Cherry, who researches inherited blindness and other visual disorders at Seattle Children’s Research Institute, in an interview. Cherry disclosed he has collaborated with Comander on research before, but played no part in the development of this treatment.

"It can improve people's lives in a way that might have been considered science fiction years ago," said Cherry. It should be noted, however, that while blind people face challenges due to inaccessibility, many live happy, fulfilled lives.

Mashable Trend Report Decode what’s viral, what’s next, and what it all means. Sign up for Mashable’s weekly Trend Report newsletter. By clicking Sign Me Up, you confirm you are 16+ and agree to our Terms of Use and Privacy Policy. Thanks for signing up!

The rare, mutated gene in afflicted patients, known as RPE65, prevents the retina, a light-sensitive tissue behind the eye, from working correctly. Specifically, the gene prevents retinal cells from properly producing proteins, resulting in deteriorating eyesight. Many patients become legally blind, and some lose all their eyesight.

Original image replaced with Mashable logoOriginal image has been replaced. Credit: Mashable

This novel gene therapy, called gene-replacement therapy, is designed to replace the mutated genes with genes that work, and accordingly, improve a patient's eyesight. Synthetic genes are first grown in a lab and then inserted into viruses commonly found in the human eye. The viruses -- whose mission is to invade eye cells and infuse genetic material into them -- are then carefully placed in the patient's retina.

These viruses, said Cherry, naturally live in our eyes and are harmless.

Because there were no other meaningful treatments available for this incurable disease, the FDA approved the treatments more rapidly than it typically does, under programs called Breakthrough Therapy and Priority Review.

These sorts of accelerated approvals require drug companies and clinicians to continue monitoring the treatments after their initial FDA approval, to ensure they're truly safe and effective enough for consumers to use. The safety warnings on the Luxturna website underscore these potential hazards, including potential eye infections and further declines in vision.

Earlier in 2017, the FDA had approved two other gene-therapy treatments for cancers, which aren't considered genetically-inherited diseases. The FDA now plans for gene therapies to play a more prominent role in combating previously untreatable diseases.

"I believe gene therapy will become a mainstay in treating, and maybe curing, many of our most devastating and intractable illnesses,” FDA Commissioner Scott Gottlieb said when announcing the approval of Luxturna.

Although gene therapies provide treatments for historically unmanageable diseases, they can be markedly more expensive than conventional treatments, especially if the disease -- such as this retinal mutation -- is rare.

The price right now is prohibitively high for most Americans: It costs $425,000, per eye. The pharmaceutical company that produces the treatment, Spark Therapeutics, notes on its website that it assists by directly contacting insurers and offers payment plans.

But Cherry hopes this gene therapy can be expanded to other similar diseases, driving down the cost of artificially producing the genes.

"We’re all in it to try and improve people's lives. So making the treatment more accessible is on everyone’s mind," said Cherry.


Featured Video For You
Google is learning how to predict heart disease by looking at your eyes

0.1217s , 9939.4140625 kb

Copyright © 2025 Powered by 【eroticism in walt whitman】To treat blindness, doctors put gene,Public Opinion Flash  

Sitemap

Top 主站蜘蛛池模板: 国产麻豆一区二区三区精品视频 | 少妇我被躁爽到高潮A片 | 人妻91无码精品一区二区内射 | 伊人久久精品无码麻豆一区 | 中文字幕韩国三级少妇在线光看 | 四虎在线视频免费观看 | 国产成人久久久精品二区三区 | 91国内偷拍久久久 | 欧洲永久精品大片ww免费网站 | 亚洲综合色一区二区三区小说 | 国产真实乱子伦新视频 | 国产三级日产三级韩国三级 | 岛国无码另类视频在线观看网址 | 成人综合国语对白 | 国产成人精品一区二区三区免费看 | 亚洲精品成人片在线观看 | 精品国产片一区二区三区 | 成年女人色毛片免费 | 精品国产亚洲日本一区二区 | 91麻豆天美精东蜜桃传媒电影在线观看 | 制服丝袜在线人妻中文字幕 | 久久久久久夜精品精品免费 | 欧美性与交视频在线观看 | 一本道亚洲精品久久 | 国产精品水嫩水嫩 | 国产又色又爽又黄的网站在线一级 | 久久精品av | 久久久久女人精品毛片九一 | 亚洲国产婷婷香蕉久久久久久 | 日本人妻人人人澡人人爽欧美a级在线观看 | 国产免费一区二区三区免费视频 | 九月色综合网 | 国产看真人毛片爱做A片 | 华人夫妻在线国产 | 久久精品综合欧美日韩久久 | 麻豆一区二区99久久久久 | 久久国产人人操人人爽 | 日日天干夜夜狠狠爱 | jizz国产丝袜18老师美女 | 国产精品亚洲欧美日韩区 | 久久精品国产日本波多野结夜 |